SNU-1

KCLB No. 00001
Name SNU-1
세포주 분양조건
서비스
수량
  • Information
  • STR data
  • Culture Morphology
  • NGS & Drug Info.
  • Culture Method
  • References
Origin stomach, gastric
Species human, asian
Tumorigenecity yes, in immunosuppressed mice
Cellular morphology lymphoblast-like
Growth pattern suspension
Histopathology adenocarcinoma
Differentiation poorly differentiated
Depositor Jae-Gahb Park, M.D.
Update date 2014-09-11
Option culture frozen
D3S1358: 16,17
vWA: 14
FGA: 22
Amelogenin: X,Y
TH01: 8,9.3
TPOX: 8,10
CSF1PO: 12,14
D5S818: 13
D13S317: 12,14
D7S820: 9,12
Freezing media RPMI1640, 52.5%; FBS, 40%; DMSO, 7.5%
Original media RPMI1640 with L-glutamine (300mg/L), 25mM HEPES and 25mM NaHCO3, 90%; fetal bovine serum (FBS), 10%
KCLB media RPMI1640 with L-glutamine (300mg/L), 25mM HEPES and 25mM NaHCO3, 90%; heat inactivated fetal bovine serum (FBS), 10%
Subculture Collect the cells into 15ml tube and centrifue, aspirate the culture medium, resuspend the pellets, dispense the cells into the culture flask
Note Penicillin-streptomycin were added to culture media (final concentration, 100 U/mL)
Populaton doubling time 26 hours
Split ratio 1:4
Media change Collect the cells and centrifuge, remove two thirds of medium, add fresh medium (depending on cell density) every 2 to 3 days
Cancer Res, 50: 2773-2780, 1990; J Nat
  • Shin KH, Yang YM, Park JG: Absence or decreased levels of the hMLH1 protein in human gastric carcinoma cell lines: implication of hMLH1 in alkylation tolerance. J Cancer Res Clin Oncol 124: 8, 421-6.
    ▶ Ref. KCLB Cell line No.'s - [ 00001, 00005, 00016, 00216, 00484, 00520, 00601, 00620, 00638, 00668, 00719 ]
  • Shin KH, Han HJ, Park JG: Growth suppression mediated by transfection of wild-type hMLH1 in human cancer cells expressing endogenous truncated hMLH1 protein. Int J Oncol 12: 3, 609-15. Mar 1998
    ▶ Ref. KCLB Cell line No.'s - [ 00001, 10247 ]
  • Kim JD, Kim JM, Pyo JO, Kim SY, Kim BS, Yu R, Han IS: Capsaicin can alter the expression of tumor forming-related genes which might be followed by induction of apoptosis of a Korean stomach cancer cell line, SNU-1. Cancer Lett 9: 120(2), 235-41. Dec 1997
    ▶ Ref. KCLB Cell line No.'s - [ 00001 ]
  • Kang MS, Kim HS, Han JA, Park SC, Kim WB, Park JG: Characteristics of human gastric carcinoma cell lines with induced multidrug resistance. Anticancer Res 17: 5A, 3531-6. Sep 1997
    ▶ Ref. KCLB Cell line No.'s - [ 00001, 00016 ]
  • Kim DK, Kim HT, Tai JH, Cho YB, Kim TS, Kim KH, Park JG, Hong WS: Pharmacokinetics and antitumor activity of a new platinum compound, cis-malonato[(4R,5R)-4,5-bis(aminomethyl)-2-isopropyl-1, 3- dioxolane]platinum(II), as determined by ex vivo pharmacodynamics. Cancer Chemother Pharmacol 37: 1-2, 1-6. 1995
    ▶ Ref. KCLB Cell line No.'s - [ 00001, 00005, 00016, 80103, 30103, {PC-9}, {PC-14} ]
  • Park IK, Kim BJ, Goh YJ, Lyu MA, Park CG, Hwang ES, Kook YH: Co-expression of urokinase-type plasminogen activator and its receptor in human gastric-cancer cell lines correlates with their invasiveness and tumorigenicity. Int J Cancer 29: 71(5), 867-73. May 1997
    ▶ Ref. KCLB Cell line No.'s - [ 00001, 00005, 21736, {Hs746T} ]
  • Bae CD, Park SE, Seong YS, Kimm SW, Park JB, Park JB: The mechanism of c-erbB-2 gene product increase in stomach cancer cell lines. J Korean Med Sci 8: 2, 153-9. Apr 1993
    ▶ Ref. KCLB Cell line No.'s - [ 00001, 00005, 00016, 30103 ]
  • Lee KS, Kim HK, Moon HS, Hong YS, Kang JH, Kim DJ, Park JG: Effects of buthionine sulfoximine treatment on cellular glutathione levels and cytotoxicities of cisplatin, carboplatin and radiation in human stomach and ovarian cancer cell lines. Korean J Intern Med 7: 2, 111-7. Jul 1992
    ▶ Ref. KCLB Cell line No.'s - [ 00001, 30106 ]
  • Park BK, Moon HR, Yu JR, Kook J, Chai JY, Lee SH: Comparative susceptibility of different cell lines for culture of Toxoplasma gondii in vitro. Korean J Parasitol 31: 3, 215-22. Sep 1993
    ▶ Ref. KCLB Cell line No.'s - [ 00001, 00016, 10034, 10081, 10185, 10240, 80103, {PC-14} ]

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