세포주 정보

SNU-487
SNU-487
KCLB NO
00487.1
Name
SNU-487
세포주 분양조건
  • 무항생제 배양
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Origin
cervix, uterine
Species
human, asian female, 38 years old,
Virus
HPV type 18
Cellular morphology
floating aggregates
Growth Pattern
suspension
Histopathology
small cell carcinoma, stage IB (FIGO)
Depositor
Jae-Gahb Park, M.D.
Option
No Antibiotics
Cell viability
87%
D3S1358
15,16
vWA
14,16
FGA
23
Amelogenin
X
TH01
9,9.3
TPOX
11
CSF1P0
11
D5S818
10
D13S317
8,12
D7S820
10,13
준비중입니다.
freeze media
RPMI1640, 52.5%; FBS, 40%; DMSO, 7.5%
original medium
RPMI1640 with L-glutamine (300mg/L), 25mM HEPES and 25mM NaHCO3, 90%; heat inactivated fetal bovine serum (FBS), 10%
kclb media
RPMI1640 with L-glutamine (300mg/L), 25mM HEPES and 25mM NaHCO3, 90%; heat inactivated fetal bovine serum (FBS), 10%
subculturing
Collect the cells into 15ml tube and centrifue, aspirate the culture medium, resuspend the pellets, dispense the cells into the culture flask
note
HPV18, E1, deleted, E2, intact; HPV 18 was presumably integrated into chromosome; HPV 18 was not detectably by Southern blot analysis; E6/E7 gene of HPV 18 was expressed., No antibiotics were added to culture media (No penicillin and streptomycin)
populaton doubling time
52 hours
splitratio
01:02
media change
Collect the cells and centrifuge, remove two thirds of medium, add fresh medium (depending on cell density) every 2 to 3 days
Ku et al., Establishment and Characterization of 12 uterine cervical-carcinoma cell lines: Common sequence variation in the E7 gene of HPV-16-positive cell lines. Int J Cancer. 1997 Jul 17; 72(2):313-320