세포주 정보

SiHa
SiHa
KCLB NO
30035
Name
SiHa
세포주 분양조건
서비스
수량
- +
Origin
cervix, uterine
Species
human female, 55 years old, Mongoloid
Tumorigenecity
Yes, in nude mice; forms poorly differentiated epidermoid carcinoma (grade III)
Isoenzyme
PGM3,1-2;PGM1,1;ES-D,2;AK-1,1;Me-2,1;GLO-1,2;G6PD,B
Cellular morphology
epithelial
Growth Pattern
monolayer
Histopathology
carcinoma, squamous cell
Oncogene
pRB+; p53 +
D3S1358
16,17
vWA
14,17
FGA
21
Amelogenin
X
TH01
6,9
TPOX
8
CSF1P0
12
D5S818
9
D13S317
11
D7S820
10
준비중입니다.
freeze media
RPMI1640, 52.5%; FBS, 40%; DMSO, 7.5%
original medium
Minimum essential medium (Eagle) in Earle's BSS with nonessential amino acids ad sodium pyruvate, 90%; heat inactivated fetal bovine serum (FBS) 10%
kclb media
Dulbecco's modified Eagle's medium, 90%; heat inactivated fetal bovine serum (FBS) 10%
subculturing
Remove medium, add fresh 0.25% trypsin solution for 3 to 5 min., remove trypsin, add fresh medium, aspirate and dispense into new flasks. Subculture every 6 to 8 days.
note
This line is reported to contain an integrated human papillomavirus type 16 genome (HPV-16, 1 to 2 copies per cell).
Baker CC et al. Structural and transcriptional analysis of human papillomavirus type 16 sequences in cervical carcinoma cell lines. J. Virol. 16: 962-967, 1987Friedl F et al. Studies on a new human cell line (Siha) derived from carcinoma of uterus.I. Its establishment and morphology. Proc.Soc.Exp.Biol.Med. 135: 543-545, 1970