세포주 정보

SNU-C2A
SNU-C2A
KCLB NO
0000C2A
Name
SNU-C2A
세포주 분양조건
서비스
수량
- +
Origin
colon; colorectal
Species
human, asian female, 43 years old
Cellular morphology
epithelial
Growth Pattern
monolayer
Histopathology
adenocarcinoma
Differentiation
poorly differentiated
Depositor
Jae-Gahb Park, M.D.
DateOfUpdated
2014-09-11
D3S1358
13
vWA
15,19
FGA
20,22
Amelogenin
X
TH01
9
TPOX
8
CSF1P0
11,14
D5S818
8,9
D13S317
9,12
D7S820
13,16
준비중입니다.
freeze media
RPMI1640, 52.5%; FBS, 40%; DMSO, 7.5%
original medium
RPMI1640 with L-glutamine (300mg/L), 25mM HEPES and 25mM NaHCO3, 90%; heat inactivated fetal bovine serum (FBS), 10%
kclb media
RPMI1640 with L-glutamine (300mg/L), 25mM HEPES and 25mM NaHCO3, 90%; heat inactivated fetal bovine serum (FBS), 10%
subculturing
Remove the supernatant and rinse with sterile PBS. Add 2mL of trypsin-EDTA (usually 0.05%) in PBS and incubate at 37oC for approximately 3 minutes (T25cm^2). Add 5ml of growth medium supplemented with 10% FBS and centrifuge. Decant the supernatant and redisperse the cancer cells by pipetting them with the growth medium.
note
This cell line was derived from a 3rd passage nude mouse xenograft of tumor fragments obtained from a patient prior to therapy. This cell line is a pseudodiploid human cell line an and has a high concentration of receptors for EGF. This cell line has lost chromosomes 11 while SNU-C2B has lost only both chromosomes 8 and 11. Penicillin-streptomycin were added to culture media (final concentration, 100 U/mL)
populaton doubling time
82 hours
splitratio
1:4
media change
Remove two thirds of medium and add fresh medium (depending on cell density) every 2 to 3 days
Cancer Res, 47: 6710-6718, 1987
  • Chung JK, Lee YJ, Kim C, Choi SR, Kim M, Lee K, Jeong JM, Lee DS, Jang JJ, Lee MC: Mechanisms related to [18F]fluorodeoxyglucose uptake of human colon cancers transplanted in nude mice. J Nucl Med 4 2 339-46 Feb 1999
    ▶ ref. kclb cell line no.'s - [ 0000C2A, 0000C4, 0000C5 ]