세포주 정보

SNU-1299
SNU-1299
KCLB NO
01299
Name
SNU-1299
세포주 분양조건
서비스
수량
- +
Origin
cervix, uterine
Species
human, asian human
Abnormal genes
HPV 16, E7 gene, codon 732, TTT->TTC (Phe to Phe), codon 789, ATT->ATC (Ile to Ile), codon 795, ACT->ACG (Thr to Thr)
Virus
HPV type 16
Cellular morphology
epithelial
Growth Pattern
monolayer
Histopathology
carcinoma, squamous cell; stage IIB (FIGO)
Depositor
Jae-Gahb Park, M.D.
Cell viability
97%
D3S1358
15,16
vWA
14,18
FGA
22
Amelogenin
X
TH01
8
TPOX
8
CSF1P0
9,10
D5S818
7,11
D13S317
11
D7S820
8,11
준비중입니다.
freeze media
RPMI1640, 52.5%; FBS, 40%; DMSO, 7.5%
original medium
RPMI1640 with L-glutamine (300mg/L), 25mM HEPES and 25mM NaHCO3, 90%; heat inactivated fetal bovine serum (FBS), 10%
kclb media
RPMI1640 with L-glutamine (300mg/L), 25mM HEPES and 25mM NaHCO3, 90%; heat inactivated fetal bovine serum (FBS), 10%
subculturing
Remove medium, add fresh 0.25 % trypsin 0.02 % EDTA solution, stand culture flask at 37
note
HPV16, E1 gene, deleted, E2 gene, deleted by PCR analysis; HPV 16 was presumably integrated into chromosome; HPV16 was not detectable by Southern blot analysis; E6/E7 gene of HPV16 was expressed by Northern analysis.
populaton doubling time
48 hours
splitratio
1:4
media change
Remove two thirds of medium and add fresh medium (depending on cell density) every 2 to 3 days
Int J Cancer. 1997 Jul 17; 7292): 313-320
  • Ku JL, Kim WH, Park HS, Kang SB, Park JG: Establishment and characterization of 12 uterine cervical-carcinoma cell lines: common sequence variation in the E7 gene of HPV-16-positive cell lines. Int J Cancer 17 72(2) 313-20 Jul 1997
    ▶ ref. kclb cell line no.'s - [ 00017, 00487, 00523, 00682, 00703, 00778, 00902, 01000, 01005, 01160, 01245, 01299 ]