세포주 정보

RBL-2H3
RBL-2H3
KCLB NO
22256
Name
RBL-2H3
세포주 분양조건
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Origin
blood; basophil
Species
rat
Strain
Wistar
Receptor
FcERI (Fc of IgE)
Cellular morphology
fibroblast
Production
histamine
Growth Pattern
monolayer
Histopathology
leukemia, chemically induced
준비중입니다.
freeze media
RPMI1640, 52.5%; FBS, 40%; DMSO, 7.5%
original medium
Minimum essential medium Eagle with 2mM L-glutamine and Earle's BSS, 85%; heat inactivated fetal bovine serum (FBS), 15%
kclb media
Dulbecco's modified Eagle's medium, 90%; heat inactivated fetal bovine serum (FBS) 10%
subculturing
Remove spent medium, add fresh 0.25% trypsin, 0.03% EDTA solution, rinse and remove trypsin. Add fresh trypsin solution (1 to 2 ml) and let the culture sit at room temperature (or at 37C) until the cells detach. Add fresh medium, aspirate and dispense into new flasks.
splitratio
1:4 to 1:8
media change
every 2 to 3 days
Kulczycki AJ et al. The interaction of IgE with rat basophilic leukemia cells. I. Evidence for specific binding of IgE. J.Exp.Med. 139: 600-616, 1974. Barsumian EL et al. IgE-induced histamine release from rat basophilic leukemia cell lines: isolation of releasing and nonreleasing clones. Eur.J.Immunol.11: 317-323, 1981Nat.New Biol. 244: 73-76, 1973